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The FDA notes that tirzepatide may cause side effects such as nausea, diarrhea, vomiting, constipation, abdominal discomfort, injection site reactions, fatigue and reflux

After eating, the body releases signals that help regulate: Hunger Fullness Appetite Blood sugar Digestion Energy use For some people with obesity, overweight or weight loss resistance, these signals may not work as predictably as they should

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